Epstein-Barr Virus Antibody Panel : 6421

Test Code

EBVB or 6421

Alias/See Also

EBV VCA IgG antibody by CLIA; EBV IgG;EBV Antibody; EBNA; EBV; EBV NA; EBV Nuclear Antigen Ab; EBV Past Infection; Epstein-Barr Nuclear Antigen Ab; Epstein-Barr Virus EBNA;EBV VCA IgM antibody by CLIA; EBV IgM

CPT Codes
86664, 86665x2

Includes

Panel includes: Epstein-Barr Virus VCA Antibody (IgM), Epstein-Barr Virus VCA Antibody (IgG), Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)

Instructions

Serum separator tube (gold top preferred) or a plain red top tube.

Transport Container

Centrifuge the serum separator tube and transport; if a plain red top tube, centrifuge and aliquot 1 mL serum (Min. 0.8 mL) into a standard transport tube.

Transport Temperature

Refrigerated.

Specimen Stability

After separation from cells: Ambient: 4 days; Refrigerated: 7 days; Frozen: 30 days (only one freeze-thaw allowed)

Methodology
Immunoassay

Setup Schedule

Monday & Wednesday & Friday

Report Available

1-4 days

Reference Range

Epstein-Barr Virus VCA Antibody (IgM)
U/mL                Interpretation
<36.00              Negative
36.00-43.99    Equivocal
>43.99              Positive

Epstein-Barr Virus VCA Antibody (IgG)
U/mL                   Interpretation
<18.00                 Negative
18.00-21.99       Equivocal
>21.99                 Positive

Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)
U/mL                    Interpretation
<18.00                  Negative
18.00-21.99        Equivocal
>21.99                  Positive

Clinical Significance

Primary infection by EBV causes infectious mononucleosis, usually a self-limiting disease in children and young adults. Infection with EBV can cause lymphoproliferative disorders including tumors. VCA-IgM is typically detectable at clinical presentation, then declines to undetectable levels within a month in young children and within 3 months in other individuals. VCA-IgG is typically detectable at clinical presentation, and persists for life. EBNA IgG typically appears during convalescence (3-4 months after clinical presentation) and remains detectable for life.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.