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Cyclosporine A, Trough, Immunoassay, Blood : 8812
Test CodeCYATRQ or 8812
Alias/See Also
Sandimmune
CPT Codes
80158
Instructions
Collect as a trough, 12 hours after last dose.
Lavender (EDTA).
Lavender (EDTA).
Transport Container
Transport 2 mL EDTA whole blood, (Min: 1 mL).
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: Unacceptable; Refrigerated: 7 days; Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted specimen.
Methodology
Immunoassay (IA)
Setup Schedule
Monday - Friday (Days only)
Report Available
1-3 days (From receipt at performing laboratory)
Reference Range
No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post-transplant, co-administration of other drugs, and drug formulation. The following trough ranges are suggested guidelines:
Kidney Transplantation 100-200 mcg/L
Other Organ Transplantation 200-300 mcg/L
Kidney Transplantation 100-200 mcg/L
Other Organ Transplantation 200-300 mcg/L
Clinical Significance
Cyclosporine (Cyclosporin A) is an immunosuppressant therapeutic agent used in the prevention of organ graft rejection. Measurement of blood levels is recommended due to the inter-individual variability of metabolism as well as the toxicity associated with excessive dosage.
Performing Laboratory
Quest Diagnostics