Alkaline Phosphatase, Bone Specific : 29498

Test Code

ALPBQ or 29498

Alias/See Also

Alkaline Phosphatase Bones, BSAP, Bone specific ALK Phos, Ostase, Alkaline Phosphatase, skeletal, Bone Specific ALK Phos

CPT Codes
84075

Instructions

Serum separator tube or plain red.

Transport Container

Centrifuge the serum separator tube and transport. If plain red, centrifuge and aliquot 1 mL serum (Min: 0.3 mL) into a standard transport tube.

Transport Temperature

Refrigerated.

Specimen Stability

Ambient: 7 days; Refrigerated: 7 days; Frozen: 60 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis, Gross lipemia, Non-serum samples, Grossly icteric.

Methodology
Immunoassay

Setup Schedule

Tuesday - Saturday

Report Available

1-2 days (From receipt at performing laboratory)

Reference Range

Adult Male Reference Ranges for Alkaline Phosphatase, Bone Specific
18-29 Years: 8.4-29.3 mcg/L
30-39 Years: 7.7-21.3 mcg/L
40-49 Years: 7.0-18.3 mcg/L
50-68 Years: 7.6-14.9 mcg/L
greater than 68 Years: Not established for this age group

Adult Female Reference Ranges for Alkaline Phosphatase, Bone Specific
18-29 Years: 4.7-17.8 mcg/L
30-39 Years: 5.3-19.5 mcg/L
40-49 Years: 5.0-18.8 mcg/L
50-76 Years: 5.6-29.0 mcg/L
greater than 76 Years: Not established for this age group
Premenopausal (35-45 Years) 5.0-18.2 mcg/L

Pediatric Reference Ranges for Alkaline Phosphatase, Bone Specific
Males (mcg/L) Females (mcg/L)
2-24 Months** 25.4-124.0 25.4-124.0
6-9 Years 41.0-134.6 41.0-134.6
10-13 Years 43.8-177.4 24.2-154.2
14-17 Years 13.7-128.0 10.5- 75.2

** Pediatric data from Int J Biol Markers (1996) 11:159-164

Clinical Significance

The Bone-Specific Alkaline Phosphatase (BSAP) assay provides a general index of bone formation and a specific index of total osteoblast activity. BSAP and osteocalcin are the most effective markers of bone formation and are particularly useful for monitoring bone formation therapies and antiresorptive therapies.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.