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Alkaline Phosphatase, Bone Specific : 29498
Test CodeALPBQ or 29498
Alias/See Also
Alkaline Phosphatase Bones, BSAP, Bone specific ALK Phos, Ostase, Alkaline Phosphatase, skeletal, Bone Specific ALK Phos
CPT Codes
84075
Instructions
Serum separator tube or plain red.
Transport Container
Centrifuge the serum separator tube and transport. If plain red, centrifuge and aliquot 1 mL serum (Min: 0.3 mL) into a standard transport tube.
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: 7 days; Refrigerated: 7 days; Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, Gross lipemia, Non-serum samples, Grossly icteric.
Methodology
Immunoassay
Setup Schedule
Tuesday - Saturday
Report Available
1-2 days (From receipt at performing laboratory)
Reference Range
Adult Male Reference Ranges for Alkaline Phosphatase, Bone Specific
18-29 Years: 8.4-29.3 mcg/L
30-39 Years: 7.7-21.3 mcg/L
40-49 Years: 7.0-18.3 mcg/L
50-68 Years: 7.6-14.9 mcg/L
greater than 68 Years: Not established for this age group
Adult Female Reference Ranges for Alkaline Phosphatase, Bone Specific
18-29 Years: 4.7-17.8 mcg/L
30-39 Years: 5.3-19.5 mcg/L
40-49 Years: 5.0-18.8 mcg/L
50-76 Years: 5.6-29.0 mcg/L
greater than 76 Years: Not established for this age group
Premenopausal (35-45 Years) 5.0-18.2 mcg/L
Pediatric Reference Ranges for Alkaline Phosphatase, Bone Specific
Males (mcg/L) Females (mcg/L)
2-24 Months** 25.4-124.0 25.4-124.0
6-9 Years 41.0-134.6 41.0-134.6
10-13 Years 43.8-177.4 24.2-154.2
14-17 Years 13.7-128.0 10.5- 75.2
** Pediatric data from Int J Biol Markers (1996) 11:159-164
18-29 Years: 8.4-29.3 mcg/L
30-39 Years: 7.7-21.3 mcg/L
40-49 Years: 7.0-18.3 mcg/L
50-68 Years: 7.6-14.9 mcg/L
greater than 68 Years: Not established for this age group
Adult Female Reference Ranges for Alkaline Phosphatase, Bone Specific
18-29 Years: 4.7-17.8 mcg/L
30-39 Years: 5.3-19.5 mcg/L
40-49 Years: 5.0-18.8 mcg/L
50-76 Years: 5.6-29.0 mcg/L
greater than 76 Years: Not established for this age group
Premenopausal (35-45 Years) 5.0-18.2 mcg/L
Pediatric Reference Ranges for Alkaline Phosphatase, Bone Specific
Males (mcg/L) Females (mcg/L)
2-24 Months** 25.4-124.0 25.4-124.0
6-9 Years 41.0-134.6 41.0-134.6
10-13 Years 43.8-177.4 24.2-154.2
14-17 Years 13.7-128.0 10.5- 75.2
** Pediatric data from Int J Biol Markers (1996) 11:159-164
Clinical Significance
The Bone-Specific Alkaline Phosphatase (BSAP) assay provides a general index of bone formation and a specific index of total osteoblast activity. BSAP and osteocalcin are the most effective markers of bone formation and are particularly useful for monitoring bone formation therapies and antiresorptive therapies.
Performing Laboratory
Quest Diagnostics