Complement, Total (CH50) : 618

Message

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Test Code

CH50T or 618

Alias/See Also

Hemolytic Complement

CPT Codes
86162

Instructions

Plain red.

Transport Container

Allow specimen to clot. Centrifuge and separate serum from cells within 1 hour of collection. Transfer 1 mL serum to a standard transport tube. (Min: 0.5 mL) Freeze immediately.

Transport Temperature

Frozen.

Specimen Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis, Lipemia, Received thawed

Methodology
Liposome

Setup Schedule

Sunday & Monday & Wednesday - Friday

Report Available

3-5 days (From receipt at performing laboratory)

Reference Range

31-60 U/mL

Clinical Significance

CH50 is a screening test for total complement activity. Levels of complement may be depressed in genetic deficiency, liver disease, chronic glomerulonephritis, rheumatoid arthritis, hemolytic anemias, graft rejection, systemic lupus erythematosis, acute glomerulonephritis, subacute bacterial endocarditis and cryoglobulinemia. Elevated complement may be found in acute inflammatory conditions, leukemia, Hodgkin's Disease, sarcoma, and Behcet's Disease.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.