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Carbamazepine and Metabolite Total/Free/Bound : 7933
Test CodeCARBFT or 7933
Alias/See Also
Tegretol
CPT Codes
80156, 80157, 80161
Includes
Total, Total metabolite, Free, Free metabolite, Bound, and Bound metabolite.
Instructions
Plain red or Lavender top tube.
Transport Container
Centrifuge plain red or lavender top tube and transfer 2 mL serum or plasma into a standard transport tube. (Min: 1.7 mL)
Transport Temperature
Refrigerated.
Specimen Stability
After separation from cells: Ambient: 14 days; Refrigerated: 14 days; Frozen: 10 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tubes (SST).
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Monday - Friday
Report Available
2-5 days (From receipt at performing laboratory)
Limitations
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range
By report.
Clinical Significance
Carbamazepine and its metabolite (10, 11-carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, it's therapeutic level should be monitored along with its metabolite in their free and protein bound states.
Performing Laboratory
Quest Diagnostics
