Carbamazepine and Metabolite Total/Free/Bound : 7933

Test Code
CARBFT or 7933


Alias/See Also
Tegretol


CPT Codes
80156, 80157

Includes
Carbamzaepine Panel includes: Total, Total metabolite, Free, Free metabolite, Bound, and Bound metabolite.


Instructions
Plain red or Lavender top tube.


Transport Container
Centrifuge plain red or lavender top tube and transfer 2 mL serum or plasma into a standard transport tube. (Min: 1.7 mL)


Transport Temperature
Refrigerated.


Specimen Stability
After separation from cells: Ambient: 14 days; Refrigerated: 14 days; Frozen: 10 months


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tubes (SST).


Methodology
Chromatography/Mass Spectrometry

Setup Schedule
Monday - Friday


Report Available
2-5 days (From receipt at performing laboratory)


Reference Range
By report.


Clinical Significance
Carbamazepine and its metabolite (10, 11-carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, it's therapeutic level should be monitored along with its metabolite in their free and protein bound states.


Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.