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Carbamazepine and Metabolite Total/Free/Bound : 7933
Test CodeCARBFT or 7933
Alias/See Also
Tegretol
CPT Codes
80156, 80157
Includes
Carbamzaepine Panel includes: Total, Total metabolite, Free, Free metabolite, Bound, and Bound metabolite.
Instructions
Plain red or Lavender top tube.
Transport Container
Centrifuge plain red or lavender top tube and transfer 2 mL serum or plasma into a standard transport tube. (Min: 1.7 mL)
Transport Temperature
Refrigerated.
Specimen Stability
After separation from cells: Ambient: 14 days; Refrigerated: 14 days; Frozen: 10 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tubes (SST).
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Monday - Friday
Report Available
2-5 days (From receipt at performing laboratory)
Reference Range
By report.
Clinical Significance
Carbamazepine and its metabolite (10, 11-carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is co-medicated with other anticonvulsants and, therefore, it's therapeutic level should be monitored along with its metabolite in their free and protein bound states.
Performing Laboratory
Quest Diagnostics