EGFR amplification by FISH : 1001049

Please provide most recent Pathology report.

MDFCPEGFRFNB or 1001049

Epidermal growth factor receptor

Tissue.

Paraffin embedded formalin fixed tissue that has been fixed in 10% neutral buffered formalin for at least 6 hours and no longer than 48 hours. Two unstained slides, with tissue of 4 microns in thickness are needed for processing, accompanied by a circled H & E clearly indicating the area to be examined.

Paraffin embedded tissue block: Ambient or on ice pack in summer. Slides: Ambient.

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Monday - Friday

Up to 7 days

Laboratory test results should always be considered in the context of clinical observations. This test was developed and its performance characteristics determined by med fusion. It has not been cleared or approved by the U.S. Food and Drug Administration
(FDA). The FDA has determined that such clearance or approval is not necessary. This test is used for clinical purposes. It should not be regarded as investigational for research. This laboratory is certified under the Clinical Laboratory Improvement Amendments
of 1988 (CLIA) as qualified to perform high complexity clinical laboratory testing.

An interpretive report will be provided.

The EGFR gene (7p12.1) is frequently overexpressed, amplified and very rarely mutated in glioblastomas that arise de novo and a close correlation between EGFR gene copy-number alterations and the level of EGFR protein expression has been reported.