A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Histone Antibodies : 37056
MessageAovid hemolysis.
Test Code
HISTOQ or 37056
CPT Codes
83516
Instructions
Overnight fasting is preferred.
Serum separator tube or plain red.
Serum separator tube or plain red.
Transport Container
Centrifuge the serum separator tube and transport. If plain red, centrifuge and aliquot 1 mL serum (Min: 0.3 mL) into a standard transport tube.
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: 24 hours; Refrigerated: 14 days; Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature.
Methodology
Enzyme Immunoassay (EIA)
Setup Schedule
Tuesday & Thursday & Saturday
Report Available
2-5 days (From receipt at performing laboratory)
Reference Range
less than 0 U Negative 1.0-1.5 U Weak Positive 1.6-2.5 U Moderate Positive greater than 2.5 U Strong Positive |
Clinical Significance
Histone antibody is present in 80-95% of patients with drug-induced Systemic Lupus Erythematosus (SLE), 20-50% of patients with idiopathic SLE, and infrequently in patients with other autoimmune connective tissue diseases.
Performing Laboratory
Quest Diagnostics