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17-Hydroxyprogesterone : 17180
Test Code17HYRQ or 17180
CPT Codes
83498
Instructions
Plain red, green (no gel) (sodium heparin), lavender (EDTA), or royal blue (EDTA).
Transport Container
Centrifuge plain red, green, lavender, or royal blue and aliquot 0.5 mL (Min: 0.25 mL) serum or plasma into a standard transport tube.
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: 48 hours; Refrigerated: 7 days; Frozen: 2 years
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples collected in SST tubes.
Methodology
Chromatography/Tandem Mass Spectrometry
Setup Schedule
Sunday - Friday
Report Available
2-5 days (From receipt at performing laboratory)
Reference Range
Effective 12/10/2018
Adult Male
18-30 Years 32-307 ng/dL
31-40 Years 42-196 ng/dL
41-50 Years 33-195 ng/dL
51-60 Years 37-129 ng/dL
Adult Female
Pre-Menopausal Mid-Follicular Phase: 23-102 ng/dL
Pre-Menopausal Surge: 67-349 ng/dL
Pre-Menopausal Mid-Luteal Phase: 139-431 ng/dL
Postmenopausal less than or equal to 45 ng/dL
Pregnancy
First Trimester 78-457 ng/dL
Second Trimester 90-357 ng/dL
Third Trimester 144-578 ng/dL
Pediatric see report
Adult Male
18-30 Years 32-307 ng/dL
31-40 Years 42-196 ng/dL
41-50 Years 33-195 ng/dL
51-60 Years 37-129 ng/dL
Adult Female
Pre-Menopausal Mid-Follicular Phase: 23-102 ng/dL
Pre-Menopausal Surge: 67-349 ng/dL
Pre-Menopausal Mid-Luteal Phase: 139-431 ng/dL
Postmenopausal less than or equal to 45 ng/dL
Pregnancy
First Trimester 78-457 ng/dL
Second Trimester 90-357 ng/dL
Third Trimester 144-578 ng/dL
Pediatric see report
Clinical Significance
17-hydroxyprogesterone is elevated in patients with congenital adrenal hyperplasia (CAH). CAH is a group of autosomal recessive diseases characterized by a deficiency of cortisol and an excess of ACTH concentration. 17-hydroxyprogesterone is also useful in monitoring cortisol replacement therapy and in evaluating infertility and adrenal and ovarian neoplasms.
Performing Laboratory
Quest Diagnostics
