17-Hydroxyprogesterone : 1015276

Test Code
17HYRQ or 1015276

CPT Codes
83498

Instructions
Plain red, green (no gel) (sodium heparin), lavender (EDTA), or royal blue (EDTA).

Transport Container
Centrifuge plain red, green, lavender, or royal blue and aliquot 0.5 mL (Min: 0.25 mL) serum or plasma into a standard transport tube.

Transport Temperature
Refrigerated.

Specimen Stability
Ambient: 48 hours; Refrigerated: 7 days; Frozen: 2 years

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples collected in SST tubes.

Methodology
Chromatography/Tandem Mass Spectrometry

Setup Schedule
Sunday - Friday

Report Available
2-5 days (From receipt at performing laboratory)

Reference Range
Effective 12/10/2018
Adult Male    
18-30 Years             32-307 ng/dL
31-40 Years            42-196 ng/dL
41-50 Years            33-195 ng/dL
51-60 Years             37-129 ng/dL

Adult Female   
Pre-Menopausal Mid-Follicular Phase:  23-102 ng/dL
Pre-Menopausal Surge:   67-349 ng/dL
Pre-Menopausal Mid-Luteal Phase:   139-431 ng/dL
Postmenopausal    less than or equal to 45 ng/dL
Pregnancy   
  First Trimester        78-457 ng/dL
  Second Trimester   90-357 ng/dL
  Third Trimester       144-578 ng/dL

Pediatric  see report

Clinical Significance
17-hydroxyprogesterone is elevated in patients with congenital adrenal hyperplasia (CAH). CAH is a group of autosomal recessive diseases characterized by a deficiency of cortisol and an excess of ACTH concentration. 17-hydroxyprogesterone is also useful in monitoring cortisol replacement therapy and in evaluating infertility and adrenal and ovarian neoplasms.


Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.