Coenzyme Q10 : 19826

Test Code
COQ10 or 19826


CPT Codes
82542

Instructions
Fasting is not required.  Patients should not take Coenzyme Q10 supplements the morning of the test.  They may take other nutritional supplements prior to testing.

Serum separator tube. Protect from light.


Transport Container
Protect from light during collection, storage, and shipment. Centrifuge serum separator ASAP and transfer 1 mL serum to an amber transport tube (preferred) or protect the transport tube from light with foil or place in an amber bag.  (Min: 0.3 mL).  Ship as soon as possible. 


Transport Temperature
Refrigerated


Specimen Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 14 days; Frozen: 6 weeks


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimen without protection from light exposure.


Methodology
Liquid Chromatography/Tandem Mass Spectrometry

Setup Schedule
Monday - Friday


Report Available
3-5 days (From receipt at performing laboratory)


Reference Range
Effective 4-13-2020:
>0.35 ug/mL (Optimal relative risk: >0.35; High relative risk: <0.36)


Clinical Significance
Coenzyme Q10 (CoQ10) is a fat soluble cofacter that is essential for energy producing metabolic pathways and for the proper functioning of the mitochondrial oxidative system. With insufficient CoQ10, the electron transfer activity of the mitochondria decreases, resulting in a net failure to produce the energy necessary to run the cell. Tissues with high energy demand have even greater demands for CoQ10. For example, heart muscle, which continually exerts a pumping action for an entire lifetime, has an immense need for the cofactor. Studies demonstrate the effectiveness of supplemental coenzyme Q10 in cardiomyopathy, myocardial dysfunction, and congestive heart failure. CoQ10 is also a powerful antioxidant like vitamins E and C, and thus serves the role of neutralizing excess free radicals. It is now well established that the control of excessive free radical activity is key in preventing/delaying the progression of degenerative diseases.


Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.