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Aldosterone/Renin Activity Ratio, LC/MS/MS : 16845
Test CodeALRNAQ or 16845
Alias/See Also
ALDO/PRA Ratio, PRA, Primary Aldosteronism , Aldosterone, LC-MS/MS, Plasma Renin Activity, LC-MS/MS
CPT Codes
82088, 84244
Includes
Panel includes: Aldosterone, Plasma Renin Activity, Aldosterone/Plasma Renin Activity Ratio
Instructions
Lavender (EDTA) tube.
Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours, then have them sit 5-15 minutes prior to collection.
Collect a mid-morning blood sample after patient has been upright (sitting, standing, or walking) for a minimum of 2 hours, then have them sit 5-15 minutes prior to collection.
Transport Container
Centrifuge lavender top ASAP and transfer 1.8 mL (Min: 0.8 mL) plasma into a standard transport tube and freeze immediately.
Transport Temperature
Frozen.
Specimen Stability
Ambient: 24 hours; Refrigerated: 24 hours; Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Moderate to gross hemolysis, plasma collected in plasma separator tube, received thawed.
Methodology
Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)
Setup Schedule
Monday - Saturday
Report Available
4-6 days (From receipt at performing laboratory)
Reference Range
Adult
Upright 8:00-10:00 A.M. less than or equal to 28 ng/dL
Upright 4:00-6:00 P.M. less than or equal to 21 ng/dL
Supine 8:00-10:00 A.M. 3-16 ng/dL
Pediatric
1-12 Months 2-70 ng/dL
1-4 Years 2-37 ng/dL
5-9 Years less than or equal to 9 ng/dL
10-13 Years less than or equal to 21 ng/dL
14-17 Years less than or equal to 35 ng/dL
Infants
Premature (31-35 Weeks) less than or equal to 144 ng/dL
Term less than or equal to 217 ng/dL
Tanner Stages
II-III Males 1-13 ng/dL
II-III Females 2-20 ng/dL
IV-V Males 3-14 ng/dL
IV-V Females 4-32 ng/dL
Plasma Renin Activity 0.25-5.82 ng/mL/h
Aldosterone/PRA Ratio 0.9-28.9 Ratio
Upright 8:00-10:00 A.M. less than or equal to 28 ng/dL
Upright 4:00-6:00 P.M. less than or equal to 21 ng/dL
Supine 8:00-10:00 A.M. 3-16 ng/dL
Pediatric
1-12 Months 2-70 ng/dL
1-4 Years 2-37 ng/dL
5-9 Years less than or equal to 9 ng/dL
10-13 Years less than or equal to 21 ng/dL
14-17 Years less than or equal to 35 ng/dL
Infants
Premature (31-35 Weeks) less than or equal to 144 ng/dL
Term less than or equal to 217 ng/dL
Tanner Stages
II-III Males 1-13 ng/dL
II-III Females 2-20 ng/dL
IV-V Males 3-14 ng/dL
IV-V Females 4-32 ng/dL
Plasma Renin Activity 0.25-5.82 ng/mL/h
Aldosterone/PRA Ratio 0.9-28.9 Ratio
Clinical Significance
The Aldosterone-renin ratio is used to screen for primary aldosteronism.
Performing Laboratory
Quest Diagnostics
