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Estriol, Serum : 34883
Test CodeESTRIQ or 34883
CPT Codes
82677
Instructions
Plain red.
Transport Container
Centrifuge plain red and aliquot 0.5 mL (Min: 0.3 mL) serum into a standard transport tube.
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: 5 days; Refrigerated: 7 days; Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples received in SST tubes
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Sunday - Friday
Report Available
3-5 days (From receipt at performing laboratory)
Limitations
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range
Adult Male: less than or equal to 0.18 ng/mL
Adult Female: (Non-pregnant) less than or equal to 0.21 ng/mL
Pregnancy:
First trimester less than or equal to 2.50 ng/mL
Second trimester less than or equal to 9.60 ng/mL
Third trimester less than or equal to 14.60 ng/mL
Adult Female: (Non-pregnant) less than or equal to 0.21 ng/mL
Pregnancy:
First trimester less than or equal to 2.50 ng/mL
Second trimester less than or equal to 9.60 ng/mL
Third trimester less than or equal to 14.60 ng/mL
Clinical Significance
The placenta converts DHEA-S produced by the fetal adrenals to Estriol and other estrogens. Estriol is useful in assessing the fetal adrenals and placenta during pregnancy. More commonly, Estriol is one of the maternal serum biochemical markers used to screen for common chromosomal trisomies, especially Down syndrome.
Performing Laboratory
Quest Diagnostics
