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HLA-B27 Antigen : 528
Test CodeHB27Q or 528
Alias/See Also
Ankylosing Spondylitis
CPT Codes
86812
Instructions
Green (no gel) sodium heparin, lavender (EDTA), or yellow (ACD Solution A or B).
Transport Container
Transport 5 mL whole blood, (Min. 1 mL).
Transport Temperature
Ambient.
Specimen Stability
Ambient: 7 days; Refrigerated: 5 days; Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis; lithium heparin (green-top) tube; clotted; received frozen.
Methodology
Flow Cytometry
Setup Schedule
Tuesday - Sunday
Report Available
2-4 days (From receipt at performing laboratory)
Reference Range
Negative
Clinical Significance
HLA-B27 is found in 90% of patients with ankylosing spondylitis and 80% in Reiter's disease. Ankylosing spondylitis affects 1 in 1000 caucasians. Ankylosing spondylitis is 10 times more common among individuals with HLA-B27 compared to individuals without this antigen.
Performing Laboratory
Quest Diagnostics
