Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G : 11368

Test Code
PAI1Q or 11368

Alias/See Also
PAI-1 Promoter  Polymorphism, PAI-4G/5G Polymorphism, Plasminogen Activator Inhibitor-1 4G/5G Polymorphism, Quest-Plasminogen Activator Inhibitor-1 4G/5G Polymorphism

CPT Codes

Lavender (EDTA), green (no gel) (sodium heparin), yellow (ACD Solution A or B), or royal blue (EDTA).

Transport Container
Transport 5 mL whole blood, (Min: 3 mL).

Transport Temperature

Specimen Stability
Ambient: 8 days; Refrigerated: 8 days; Frozen: Unacceptable

Polymerase Chain Reaction and Detection

Setup Schedule
Wednesday & Saturday

Report Available
6-10 days (From receipt at performing laboratory)

This test was developed and its performance characteristics have been determined by Quest Diagnostics. Performance characteristics refer to the analytical performance of the test.

Reference Range
See Laboratory Report.

Clinical Significance
Plasma plasminogen activator inhibitor, PAI-1 is a major inhibitor of fibrinolysis. The 4G variant (AF386492.2:g.837del) in the PAI-1 (Serpine 1) gene promoter region is associated with an increase in the level of PAI-1 in plasma. Increased levels of PAI-1 in plasma may increase the risk for arterial and venous thrombosis, myocardial infarction, and progression of atherosclerosis and also recurrent spontaneous abortion.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.