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Nicotine and Cotinine, Urine : 90646
Test CodeUNICOT or 90646
CPT Codes
80323
Instructions
Random urine.
Transport Container
Transport 1 mL urine with no additives or preservatives. (Min: 0.5 mL) Submit specimen in transport tube.
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: 72 hours; Refrigerated: 21 days; Frozen: 30 days
Methodology
Liquid Chromatography/Mass Spectrometry
Setup Schedule
Monday & Wednesday & Friday
Report Available
4 days (From receipt at performing laboratory)
Reference Range
Nicotine
Smokers 200-700 ng/mL
Nonsmokers less than or equal to 7 ng/mL
Cotinine
Smokers 300-1300 ng/mL
Nonsmokers less than or equal to 20 ng/mL
Smokers 200-700 ng/mL
Nonsmokers less than or equal to 7 ng/mL
Cotinine
Smokers 300-1300 ng/mL
Nonsmokers less than or equal to 20 ng/mL
Clinical Significance
This assay is used for the detection of nicotine and cotinine in urine to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately forty minutes; Its presence may indicate recent tobacco exposure. Cotinine, the major nicotine metabolite, has a half-life of 24 hours and is detectable for several days after cessation of tobacco exposure.
Performing Laboratory
Quest Diagnostics
