Mycoplasma pneumoniae Antibodies (IgG, IgM) : 34127

Test Code
MPNEU or 34127

Alias/See Also
Atypical pneumonia; Walking pneumonia

CPT Codes
86738x2

Instructions
Serum separator tube.

Transport Container
Centrifuge serum separator tube and transport, 1 mL serum (Min: 0.2 mL).

Transport Temperature
Refrigerated.

Specimen Stability
After separation from cells: Ambient: 4 days; Refrigerated: 7 days; Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis. Grossly lipemic. Icteric.

Methodology
Immunoassay (IA)

Setup Schedule
Sunday - Saturday

Report Available
1-3 days (From receipt at performing laboratory)

Limitations
IgM antibody testing is valuable for early diagnosis in children; in adults, paired sera for specific IgG and IgM are generally required together with PCR. Specific IgM antibodies are often absent in reinfections; specific IgA might be quite useful in this circumstance.

Reference Range
M. pneumoniae Ab (IgG)
less than or equal to 0.90 Negative
0.91-1.09 Equivocal
greater than or equal to 1.10 Positive

M. pneumoniae Ab (IgM)
Negative less than 770 U/mL
Low positive 770-950 U/mL
Positive greater than 950 U/mL

Clinical Significance
Mycoplasma are the smallest of the free-living organisms. M. pneumoniae causes approximately 10-20% of all cases of pneumonia. These pneumonias that can affect otherwise healthy individuals, are commonly referred to as ''walking'' and ''atypical'' pneumonias.

Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.