Saccharomyces cerevisiae Antibodies (ASCA) (IgA, IgG) : 1001669

Test Code
SACABS or 1001669

Alias/See Also
IBD, Inflammatory Bowel Disease, ASCA

CPT Codes
86671 x2

Instructions
Serum separator tube.

Transport Container
Centrifuge serum separator tube and transport, 2 mL serum (Min: 0.6 mL).

Transport Temperature
Refrigerated.

Specimen Stability
After separation from cells: Ambient: 14 days; Refrigerated: 21 days; Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, Lipemia.

Methodology
Immunoassay

Setup Schedule
Tuesday & Thursday & Saturday

Report Available
1-4 days (From receipt at performing laboratory)

Reference Range
ASCA IgA
less than or equal to 20.0 U Negative
20.1-24.9 U Equivocal
greater than or equal to 25.0 U Positive

ASCA IgG
less than or equal to 20.0 U Negative
20.1-29.9 U Equivocal
greater than or equal to 30.0 U Positive


Clinical Significance
Antibodies to Saccharomyces cerevisiae are found in approximately 75% of patients with Crohn's disease, 15% of patients with ulcerative colitis, and 5% of the healthy population.  High titers of antibody increase the likelihood of disease, specifically Crohn's disease, and are associated with more aggressive disease.

Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.