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Saccharomyces cerevisiae Antibodies (ASCA) (IgA, IgG) : 17609
Test CodeSACABS or 17609
Alias/See Also
IBD, Inflammatory Bowel Disease, ASCA
CPT Codes
86671 x2
Instructions
Serum separator tube.
Transport Container
Centrifuge serum separator tube and transport, 2 mL serum (Min: 0.6 mL).
Transport Temperature
Refrigerated.
Specimen Stability
After separation from cells: Ambient: 14 days; Refrigerated: 21 days; Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, Lipemia.
Methodology
Immunoassay
Setup Schedule
Tuesday & Thursday & Saturday
Report Available
1-4 days (From receipt at performing laboratory)
Reference Range
ASCA IgA
less than or equal to 20.0 U Negative
20.1-24.9 U Equivocal
greater than or equal to 25.0 U Positive
ASCA IgG
less than or equal to 20.0 U Negative
20.1-29.9 U Equivocal
greater than or equal to 30.0 U Positive
less than or equal to 20.0 U Negative
20.1-24.9 U Equivocal
greater than or equal to 25.0 U Positive
ASCA IgG
less than or equal to 20.0 U Negative
20.1-29.9 U Equivocal
greater than or equal to 30.0 U Positive
Clinical Significance
Antibodies to Saccharomyces cerevisiae are found in approximately 75% of patients with Crohn's disease, 15% of patients with ulcerative colitis, and 5% of the healthy population. High titers of antibody increase the likelihood of disease, specifically Crohn's disease, and are associated with more aggressive disease.
Performing Laboratory
Quest Diagnostics
