Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers : 37503

Test Code
TYPGM or 37503

Alias/See Also
Rickettsia typhi; Rickettsia prowazeki; Typhus Fever; Murine Typhus; Maurine typhus; Brill-Zinsswe disease

CPT Codes
86757x2

Includes
If Rickettsia (Typhus Fever) screen is detected, IgG or IgM, the appropriate Titer will be performed at an additional charge (CPT code(s): 86757 for each titer performed). (If reflex: non-orderables 37503-2 or 37503-3)

Instructions
Serum separator tube.

Transport Container
Centrifuge serum separator tube and transport, 1 mL serum (Min: 0.2 mL).

Transport Temperature
Refrigerated.

Specimen Stability
After separation from cells: Ambient: 7 days; Refrigerated: 14 days; Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis. Gross lipemia.

Methodology
Immunofluorescence Assay (IFA)

Setup Schedule
Monday - Friday

Report Available
1-4 days (From receipt at performing laboratory)

Reference Range
                           Screen                               Titer
R. typhi IgG    Not detected                 less than 1:64
R. typhi IgM    Not detected                 less than 1:64


Clinical Significance
Antigen specific IgG and IgM titers allow rapid diagnosis of infection by one or more of the typhus fever group of rickettsial agents. This group includes Rickettsia typhi (endemic or maurine typhus) R. prowazeki (epidemic typhus), and Brill-Zinsswe disease caused by reactivation of latent R. prowazeki.

Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.