von Willebrand Antigen, Multimeric Analysis : 1015183

Message
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Test Code
VWAGQ or 1015183

Alias/See Also
Multimeric Analysis, vW Factor Multimeric, vWF, vWF Multimer

CPT Codes
85247

Instructions
Lt. blue (3.2% sodium citrate).

Transport Container
Centrifuge light blue-top tube 15 minutes at approx. 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer 1 mL (Min: 0.2 mL) platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (less than 10,000/mcl). Freeze immediately.

Note: Storage of whole blood at refrigerated temperatures prior to processing may lead to cryoprecipitate formation and falsely low Factor VIII and von Willebrand Factor studies.

Transport Temperature
Frozen.

Specimen Stability
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months (-70 C)

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Thawed plasma, Received room temperature or refrigerated.

Methodology
Electrophoresis

Setup Schedule
Monday - Friday

Report Available
4-8 days (From receipt at performing laboratory)

Reference Range
Normal

Clinical Significance
von Willebrand Disease is the most common hereditary bleeding disorder and it may also be acquired. Von Willebrand Factor (VWF) is critical for normal hemostasis; mediating platelet adhesion to the damaged endothelium and protecting Factor VIII from proteolytic degradation in circulation. VWFMultimeric Analysis is used to assist in categorizing disease subtype.

Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.