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TRAb (TSH Receptor Binding Antibody) : 38683
Test CodeTBIIQ or 38683
Alias/See Also
TBII; Anti-Thyrotropin; Anti-TSHR; Thyrotropin Receptor Antibody, TRAb; TSH Receptor Antibody; TSH Receptor Blocking Antibody
CPT Codes
83520
Instructions
Serum separator tube or plain red.
Transport Container
Allow serum to clot at room temperature. Serum must be separated from the cells or gel barrier within 1 hour of collection and 1 mL serum (Min: 0.5 mL) aliquoted into a standard transport tube.
Transport Temperature
Refrigerated.
Specimen Stability
Ambient: 7 days; Refrigerated: 14 days; Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis. Serum received in a gel barrier tube or on the cells.
Methodology
Enzyme Linked Immunosorbent Assay (ELISA)
Setup Schedule
Monday & Wednesday & Friday
Report Available
3-5 days (From receipt at performing laboratory)
Reference Range
Effective 1/27/2020
< or = 2.00 IU/L
< or = 2.00 IU/L
Clinical Significance
Measurement of TRAb is used to diagnose and manage Graves' disease, neonatal hypothyroidism, and postpartum thyroid dysfunction. TRAb, which measures the ability of antibodies to inhibit TSH binding to its receptor, reflects the presence of either or both the stimulatory and inhibitory immunoglobulin classes.
Performing Laboratory
Quest Diagnostics
