Metanephrines, Fractionated, LC/MS/MS, Random Urine : 1016516

Test Code
UMETRN or 1016516


Alias/See Also
Normetanephrine, Metanephrines


CPT Codes
83835, 82570

Includes
Includes: Metanephrine, Normetanephrine, Total Metanephrines, Creatinine


Instructions
It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.

Random urine.


Transport Container
Transfer a 5 mL aliquot from a well-mixed random collection to a transport container. (Min: 1.5 mL) Record total volume on transport container and test request form. Urine with a pH of 6 or less can be transported without preservatives if transported within 48 hours of the completion of collection. If longer than 48 hours, adjust the pH of the Urine with 6 N HCl to pH <3 OR send unpreserved urine frozen.


Transport Temperature
Refrigerated or Frozen.


Specimen Stability
Ambient: 10 days (preserved); Refrigerated: 48 hours (unpreserved and pH < or = 6), 14 days (preserved); Frozen: 30 days (unpreserved), 90 days (preserved)


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Urine collected with boric acid.


Methodology
Chromatography/Mass Spectrometry

Setup Schedule
Tuesday - Saturday


Report Available
3-4 days (From receipt at performing laboratory)


Limitations
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.


Reference Range
By report.


Clinical Significance
Test is useful in the evaluation of pheochromocytoma.


Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.