Metanephrines, Fractionated, LC/MS/MS, 24-Hour Urine : 1016511

UMET24 or 1016511

Normetanephrine, Metanephrines

Includes: Metanephrine, Normetanephrine, Total Metanephrines

It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.

24-hour urine. Refrigerate 24-hour specimen during collection.

Transfer a 5 mL aliquot from a well-mixed 24-hour collection to a transport container. (Min: 1.5 mL) Record total volume on transport container and test request form. Urine with a pH of 6 or less can be transported without preservatives if transported within 48 hours of the completion of collection. If longer than 48 hours, adjust the pH of the Urine with 6 N HCl to pH <3 OR send unpreserved urine frozen.

Refrigerated or Frozen.

Ambient: 10 days (preserved); Refrigerated: 48 hours (unpreserved-with pH < or =  6), 14 days (preserved); Frozen:  30 days (unpreserved), 90 days (preserved)

Urine collected in boric acid.

Monday - Saturday

2-4 days (From receipt at performing laboratory)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

By report.

Test is useful in the evaluation of pheochromocytoma.