Metanephrines, Fractionated, LC/MS/MS, 24-Hour Urine : 1016511

Test Code
UMET24 or 1016511

Alias/See Also
Normetanephrine, Metanephrines

CPT Codes

Includes: Metanephrine, Normetanephrine, Total Metanephrines

It is preferable for the patient to be off medications for three days prior to collection. Patient should avoid tobacco, tea, coffee, for three days prior to specimen collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.

24-hour urine. Refrigerate 24-hour specimen during collection.

Transport Container
Transfer a 5 mL aliquot from a well-mixed 24-hour collection to a transport container. (Min: 1.5 mL) Record total volume on transport container and test request form. Urine with a pH of 6 or less can be transported without preservatives if transported within 48 hours of the completion of collection. If longer than 48 hours, adjust the pH of the Urine with 6 N HCl to pH <3 OR send unpreserved urine frozen.

Transport Temperature
Refrigerated or Frozen.

Specimen Stability
Ambient 7 days (preserved); Refrigerated: 48 hours (unpreserved), 8 days (preserved); Frozen: 30 days

Chromatography/Mass Spectrometry

Setup Schedule
Tuesday - Saturday

Report Available
3-4 days (From receipt at performing laboratory)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range
By report.

Clinical Significance
Test is useful in the evaluation of pheochromocytoma.

Performing Laboratory
Quest Diagnostics

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.