| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Anti-Nuclear Antibodies, IFA, with Reflex to Multiplex Antibody Cascade : 1003672
Test CodeANACAS or 1003672
Alias/See Also
Autoantibody Testing; ANA; SSA; SSB; RNP; SMITH; Jo-1; Scl-70; Centromere; Chromatin; Ribosomal P; SmRNP; ds DNA; dsDNA
CPT Codes
86038
Includes
Cascades to Stage 1 if ANA is positive: Chromatin, ds DNA multiplex flow, RNP, SMITH, Sm RNP; if Stage 1 antibodies are negative then cascades to Stage 2: Jo-1, Scl-70, SSA, SSB; if Stage 2 antibodies are negative then cascades to Stage 3: Centromere, Ribosomal P antibodies. Each Stage of the Cascade is performed at an additonal charge (if reflex to Stage 1 then add CPT code(s) 86235x4, 86225, if reflex to Stage 2 then add CPT code(s): 86235x4, if reflex to Stage 3 then add CPT code(s): 86235, 83516.) (If reflex to Cascade, non-orderable code ANASB 1004264 added will be added.)
Instructions
Serum separator tube (gold top preferred) or a plain red top tube.
Transport Container
Centrifuge the serum separator tube and transport; if a plain red top tube, centrifuge and aliquot serum (Min. 1.5 mL) into a standard transport tube.
Transport Temperature
Refrigerated.
Specimen Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 7 days; Frozen: 3 months if frozen within 24 hours
Methodology
Immunofluorescence Assay (IFA) ; if cascade then Multiplex flow Immunoassay
Setup Schedule
Monday - Saturday
Report Available
1-3 days
Reference Range
ANA Screen: Negative
All auto-antibodies : Negative with the exception of dsDNA.
dsDNA :
Negative <or = 4 IU/mL
Indeterminate 5-9 IU/mL
Positive > or = 10 IU/mL
All auto-antibodies : Negative with the exception of dsDNA.
dsDNA :
Negative <or = 4 IU/mL
Indeterminate 5-9 IU/mL
Positive > or = 10 IU/mL
Clinical Significance
Used as an aid in the diagnosis of systemic autoimmune diseases.
Performing Laboratory
med fusion
