Neuron Specific Enolase : 34476

Test Code
NEUSEQ or 34476

CPT Codes
86316

Instructions
Serum separator tube or plain red.

Transport Container
Centrifuge the serum separator tube and transport. If plain red, centrifuge and aliquot 1 mL serum (Min: 0.2 mL) into a standard transport tube.

Transport Temperature
Refrigerated.

Specimen Stability
Ambient: 7 days; Refrigerated: 14 days; Frozen: 30 days

Methodology
Immunoassay (IA)

Setup Schedule
Tuesday & Thursday & Saturday

Report Available
1-4 days (From receipt at performing laboratory)

Limitations
This test was developed and its performance characteristics have been determined by Quest Diagnostics. Performance characteristics refer to the analytical performance of the test.

Reference Range
Adult: less than 10.8 ng/mL

Clinical Significance
Elevated levels of serum NSE are reported in patients with small cell carcinomas primarily of lung origin. Patients with neuroblastomas may also have high levels of NSE. Serum NSE can be used to monitor recurrence or progression of tumor in these cancer patients. Daily serial monitoring of serum NSE may also be used in comatose patients to assess neuronal damage. High NSE levels in comatose patients at 24hr and 48hr post cardio-pulmonary resusitation have been associated with poor outcome. Hemolysis can cause false positive results.

Performing Laboratory
Quest Diagnostics



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.