Solid TumorSEQ™

Test Code

STMSEQ or 14309

CPT Codes
0379U

Preferred Specimen

1 formalin-fixed, paraffin-embedded block or
10 unstained slides (5 minimum) collected in a slide holder

Instructions

Ship ambient or on ice pack in summer.

For formalin-fixed, paraffin-embedded block and slides a pathology report must be submitted with sample. Do not reject.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Acceptable
Refrigerated: Acceptable
FrozenL Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Do not reject, send to laboratory for testing assessment

Methodology
Next Generation Sequencing

Setup Schedule

Sun, Tues, Thurs

Report Available

7-10 days

Limitations

**This test is not available for Wyoming patient testing**

Reference Range

See Laboratory Report

Clinical Significance

The 523-gene comprehensive genomic profiling panel is intended to help oncologists deliver precision medicine by providing personalized genomic analysis of a patient’s tumor tissue. This comprehensive panel offers the opportunity for a broader scope of genomic information compared to single gene tests or smaller panels. For example, it may be useful for patients with limited or ill-defined treatment options and for those considering clinical trials. This panel uses next-generation sequencing to detect mutations present in DNA and RNA extracted from formalin-fixed, paraffin embedded (FFPE) tissue sections of solid tumors. The test is designed to detect single nucleotide variants (SNVs) and small insertions/deletions, as well as whole-gene copy number alterations, translocations, and splice site variants in a select group of genes. Microsatellite instability (MSI) and tumor mutation burden (TMB) are also evaluated.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.