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Fibrinogen Activity, Clauss : 461
Test CodeFIBRGN or 461
CPT Codes
85384
Transport Container
Draw blood in a light blue-top tube containing 3.2% sodium citrate. Correct ratio of blood to citrate is critical. Do not overfill or underfill. Mix gently by inverting 3-4 times.
For non-heparinized patients, maintain specimen at room temperature. Do not uncap. Non-heparinized patients are stable up to 72 hours at room temperature. Heparinized patients are stable for 24 hours at room temperature.
If testing cannot be completed within stability limits, centrifuge 15 minutes at 1500g within one hour of collection. Transfer plasma to a transport tube and freeze immediately. Transport on dry ice.
For non-heparinized patients, maintain specimen at room temperature. Do not uncap. Non-heparinized patients are stable up to 72 hours at room temperature. Heparinized patients are stable for 24 hours at room temperature.
If testing cannot be completed within stability limits, centrifuge 15 minutes at 1500g within one hour of collection. Transfer plasma to a transport tube and freeze immediately. Transport on dry ice.
Transport Temperature
Room temperature: 3.2% sodium citrate (light blue-top) tube
Frozen: Plasma in transport tube
Frozen: Plasma in transport tube
Specimen Stability
Whole blood
Room temperature: 72 hours (non-heparinized)
Platelet-poor plasma
Frozen: 30 days
Room temperature: 72 hours (non-heparinized)
Platelet-poor plasma
Frozen: 30 days
Methodology
Photometry/Optical, Clauss
FDA Status
FDA
Setup Schedule
Sunday - Saturday
Report Available
1 day
Reference Range
175-425 mg/dL
Critical Vaiue: <50 mg/dL
Critical Vaiue: <50 mg/dL
Clinical Significance
The conversion of fibrinogen to fibrin is critical to normal hemostasis. Deficiency can produce mild to severe bleeding disorders.
Performing Laboratory
med fusion