| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Topiramate : 30965
Test CodeTOPIRE or 30965
CPT Codes
80201
Instructions
Draw at peak (2-4 hours after dose) or trough (0.5-1 hour before dose) at steady state
Transport Container
Preferred Specimens
1 mL serum collected in a red top tube (no gel) or no additive (royal blue-top) tube or 1 mL plasma collected in a lithium heparin (green-top) tube
Alternative Specimens
Plasma collected in: Sodium heparin lead-free (tan-top) tube or sodium heparin (green-top) tube
Minimum Volume
0.5 mL
1 mL serum collected in a red top tube (no gel) or no additive (royal blue-top) tube or 1 mL plasma collected in a lithium heparin (green-top) tube
Alternative Specimens
Plasma collected in: Sodium heparin lead-free (tan-top) tube or sodium heparin (green-top) tube
Minimum Volume
0.5 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 7 days; Refrigerated: 14 days; Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gel barrier/Serum Separator Tube (SST®)
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Tuesday - Saturday
Report Available
2-4 days
Reference Range
Dose (mg) Peak (mcg/mL) Trough (mcg/mL)
100 6.5-9.2 4.5-6.6
200 12.0-16.0 8.0-12.0
400 20.0-30.0 14.0-20.0
Clinical Significance
Topiramate is an anticonvulsant used as an adjunctive treatment of partial-onset epilepsy. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity.
Performing Laboratory
med fusion
