Rufinamide : 16296

Test Code
RUFIN or 16296


CPT Codes
80210

Instructions
Patient Preparation:  A trough specimen is preferred. Collect sample within 1 hour prior to next dose.          
 
Do not use gel barrier tubes.


Transport Container
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
  
Minimum Volume
0.5 mL

Alternative Specimen: Plasma collected in EDTA (lavender-top) tube


Transport Temperature
Room temperature.


Specimen Stability
Room temperature: 7 days; Refrigerated: 30 days; Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)


Methodology
Chromatography/Mass Spectrometry

Setup Schedule
Wednesday, Saturday


Report Available
2-5 days


Reference Range
Maintenance therapy with 45 mg/kg (approximately 1600 mg) daily Rufinamide resulted in plasma concentrations ranging from 5.0-55.0 mcg/mL


Clinical Significance
Rufinamide is an antiepileptic indicated for adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in children and adults. As multiple antiepileptics may be administered, it may be important to (1) optimize therapy, (2) monitor compliance, and (3) avoid toxicity.


Performing Laboratory
med fusion



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.