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Rufinamide : 16296
Test CodeRUFIN or 16296
CPT Codes
80210
Instructions
Patient Preparation: A trough specimen is preferred. Collect sample within 1 hour prior to next dose.
Do not use gel barrier tubes.
Do not use gel barrier tubes.
Transport Container
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Alternative Specimen: Plasma collected in EDTA (lavender-top) tube
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.5 mL
Alternative Specimen: Plasma collected in EDTA (lavender-top) tube
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 7 days; Refrigerated: 30 days; Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Wednesday, Saturday
Report Available
2-5 days
Reference Range
Maintenance therapy with 45 mg/kg (approximately 1600 mg) daily Rufinamide resulted in plasma concentrations ranging from 5.0-55.0 mcg/mL
Clinical Significance
Rufinamide is an antiepileptic indicated for adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in children and adults. As multiple antiepileptics may be administered, it may be important to (1) optimize therapy, (2) monitor compliance, and (3) avoid toxicity.
Performing Laboratory
med fusion