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Amiodarone : 36721
Test CodeAMIODE or 36721
CPT Codes
80151
Instructions
Centrifuge and immediately separate serum or plasma specimen from the cells into a clean transport tube. Do not use gel barrier/serum separator tube (SST).
Transport Container
Preferred Specimen
3 mL serum in a red-top tube (no gel)
Minimum Volume
1 mL
Alternative Specimen:
Plasma collected in EDTA (lavender-top) tube, sodium heparine (green-top tube) or lithium heparin (green-top) tube
3 mL serum in a red-top tube (no gel)
Minimum Volume
1 mL
Alternative Specimen:
Plasma collected in EDTA (lavender-top) tube, sodium heparine (green-top tube) or lithium heparin (green-top) tube
Transport Temperature
Refrigerated.
Specimen Stability
Room temperature: 48 hours; Refrigerated: 4 days; Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis; Lipemia; Gel barrier / Serum Separator Tube (SST®)
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Setup Schedule
Tuesday, Thursday, Saturday
Report Available
2-4 days
Reference Range
Amiodarone 1.5-2.5 mcg/mL
Desethylamiodarone 1.5-2.5 mcg/mL
Toxic >2.5 mcg/mL
Toxic effects have been observed at levels as low as 2.0 mcg/mL
Clinical Significance
Amiodarone is an antiarrhythmic drug. Therapeutic drug monitoring is useful to monitor compliance and avoid toxicity.
Performing Laboratory
med fusion