Protein Electrophoresis, Total Protein, Random Urine : 8525

Test Code
UPERAN or 8525


CPT Codes
82570, 84156, 84166

Transport Container
Preferred Specimen
25 mL random urine in an unpreserved, plastic urine container

Minimum Volume
15 mL
  
Submit a first morning voided specimen if possible.


Transport Temperature
Room temperature.


Specimen Stability
Room Temperature: 4 days; Refrigerated: 5 days; Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Acidified Urine


Methodology
Electrophoresis, Spectrophotometry

Setup Schedule
Monday, Wednesday, Friday


Report Available
2-5 days


Reference Range
See Laboratory Report


Clinical Significance
Urine protein electrophoresis (UPEP) is used to analyze the protein content in urine. The proteins are separated into five major components: albumin, alpha‐1, alpha‐2, beta and gamma. Interpretation of elevations, decreases or visual changes in different components and/or associated patterns can provide information on various disease states including inflammatory diseases, autoimmune diseases, different types of kidney injury, plasma cell disorders and cancers. UPEP is used to evaluate an individual with symptoms associated with potential monoclonal gammopathy. This test can help with initial diagnosis as well as monitoring disease progression and treatment effectiveness. The use of 24‐hour urine collection (vs random urine) is recommended by the National Comprehensive Cancer Network Panel as one of the tests for diagnosis for multiple myeloma and for monitoring response to treatment.


Performing Laboratory
med fusion



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.