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Copper, RBC : 3481
Test CodeCOPRRB or 3481
CPT Codes
82525
Instructions
Carefully clean skin prior to venipuncture. Avoid worksite collection.
Red blood cells trace metal: Use the EDTA trace metal-free (royal blue-top) tube for RBC trace metal testing.
Packed cells: centrifuge to separate plasma from RBC's and discard plasma. Transfer RBC's to a plastic transfer tube from a Quest Diagnostics (trace element and metal free) collection kit or transfer to a transport tube.
Red blood cells trace metal: Use the EDTA trace metal-free (royal blue-top) tube for RBC trace metal testing.
Packed cells: centrifuge to separate plasma from RBC's and discard plasma. Transfer RBC's to a plastic transfer tube from a Quest Diagnostics (trace element and metal free) collection kit or transfer to a transport tube.
Transport Container
Preferred Specimen
0.5 mL red blood cells collected in an EDTA trace metal-free (royal blue-top) tube
Alternative Specimens
Red blood cells collected in: EDTA (lavender-top), sodium heparin trace metal-free (royal blue-top), sodium heparin (green-top), sodium heparin lead-free (tan-top), or lithium heparin (green-top) tube
Minimum Volume
0.3 mL
0.5 mL red blood cells collected in an EDTA trace metal-free (royal blue-top) tube
Alternative Specimens
Red blood cells collected in: EDTA (lavender-top), sodium heparin trace metal-free (royal blue-top), sodium heparin (green-top), sodium heparin lead-free (tan-top), or lithium heparin (green-top) tube
Minimum Volume
0.3 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 10 days; Refrigerated: 10 days; Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis; Clotted
Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
Setup Schedule
Monday - Saturday
Report Available
1-4 days
Reference Range
0.53-0.91 mg/L
Clinical Significance
Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is distributed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Copper concentrations increase in acute phase reactions. Copper concentrations are decreased with nephrosis, malabsorption, and malnutrition. Copper concentrations are also useful to monitor patients, especially preterm newborns, on nutritional supplementation. Results of copper are often interpreted together with ceruloplasmin.
Performing Laboratory
med fusion
