Copper : 363

Test Code

COPRSE or 363

CPT Codes
82525

Instructions

Separate serum or plasma from cells within two hours. Transfer separated plasma/serum to a plastic acid-washed or metal-free vial.

Transport Container

Preferred
2 mL plasma collected in an EDTA (royal blue-top) tube or heparin (royal blue-top) tube

Alternative Specimen
Serum collected in: No additive (royal blue-top) tube

Minimum Volume: 0.7 mL

Transport Temperature

Room temperature.

Specimen Stability

Room temperature: 5 days; Refrigerated: 10 days; Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis; Serum or plasma not separated from cells; Samples submitted in non-trace metal or non-acid washed containers

Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)

Setup Schedule

Monday - Saturday

Report Available

1-4 days

Reference Range

Reference Range

≤5 Months 38-104 mcg/dL

6-11 Months 24-152 mcg/dL

12 Months-23 Months 76-193 mcg/dL

1-3 Years 87-187 mcg/dL

4-5 Years 56-191 mcg/dL

6-9 Years 117-181 mcg/dL

10-13 Years 87-182 mcg/dL

14-17 Years 75-187 mcg/dL

≥18 Years 70-175 mcg/dL

Clinical Significance

Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Copper concentrations increase in acute phase reactions and during the third trimester of pregnancy. Copper concentrations are decreased with nephrosis, malabsorption, and malnutrition. Copper concentrations are also useful to monitor patients, especially preterm newborns, on nutritional supplementation. Results of copper are often interpreted together with ceruloplasmin.

Performing Laboratory
med fusion

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.