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Tacrolimus, Highly Sensitive, LC/MS/MS : 70007
Test CodeTACR or 70007
Alias/See Also
FK506,Prograf
CPT Codes
80197
Instructions
Collect specimen 1 hour prior to next dose (12 hour trough)
Transport Container
Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
2 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
Transport Temperature
Room temperature.
Specimen Stability
Room temperature: 7 days; Refrigerated: 7 days; Frozen: 60 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted Specimen
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Setup Schedule
Monday - Saturday
Report Available
1-2 days
Reference Range
No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post-transplant, co-administration of other drugs, and drug formulation. The following trough range is a suggested guideline: 5.0-20.0 mcg/L
Clinical Significance
Tacrolimus is an immunosuppressant drug which has been shown to be effective for the treatment of rejection following transplantation.
Performing Laboratory
med fusion
