Adenosine Deaminase, RBC

Test Code

39148

Alias/See Also

LAB1373

CPT Codes
82657<br><strong>This test is not available for New York patient testing.</strong>

Preferred Specimen

1 mL whole blood collected in an EDTA (lavender-top or pink-top) or sodium or lithium heparin (green-top) tube

Minimum Volume

1 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 15 days
Refrigerated: 15 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis

Methodology
Kinetic Spectrophotometry

FDA Status
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Setup Schedule

Set up: Sun, Tues, Thurs; Report available: 2-5 days

Reference Range

400-900 mU/g Hb

Clinical Significance

Adenosine Deaminase (ADA) deficiency is an autosomal recessive disorder of purine metabolism primarily affecting lymphocyte development, viability, and function. Affected individuals have less than 1 percent of normal ADA catalytic activity in red cell hemolysates. ADA deficiency is the cause of 20-30 percent of SCID cases. If the patient has been recently transfused, ADA deficiency may be masked; interpret results with caution. Heterozygotes cannot be identified by this test.

Performing Laboratory
ARUP
500 Chipeta Way
Salt Lake City, UT 84108

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.