ACETAMINOPHEN LEVEL

Test Code

LAB43

CPT Codes
80307

Preferred Specimen

One 6mL Red Top tube
Pediatric: One Red Top microtainer

Other Acceptable Specimens

Dark Green top tube

Instructions

Sample must be centrifuged within 2 hours of collection. Serum/plasma must be removed from the red cells and put into aliquot tubes following centrifugation.

Transport Temperature

Refrigerated

Specimen Stability

Centrifuge within 2 hours of collection
Ambient: 24 hours
Refrigerated: 24 days
Frozen: 50 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Samples drawn in a tube with a separator gel will be rejected. The separator gel may cause falsely lower results.

Methodology
Enzymatic/colorimetric

Setup Schedule

Sunday-Saturday

Reference Range

Therapeutic: 10-30 ug/mL
Hepatotoxic:
4 hours post-ingestion: >150 ug/mL
8 hours post-ingestion: >75 ug/mL
12 hours post-ingestion: >40 ug/mL
Critical value: > 120 ug/mL

Clinical Significance

See Rumack-Matthew Nomogram for overdose interpretation/ treatment guidelines. Acetominophen levels are drawn when toxicity is suspected. In an acute overdose, levels are drawn 4 and 24 hours after presentation. If ingestion was >4 hours before presentation or the time of ingestion is
unknown, levels are drawn immediately. Consider monitoring liver function tests, bilirubin, and PT/INR in cases of acetominophen toxicity.

Performing Laboratory
West Virginia University Hospital, Inc.
Berkeley Medical Center
Braxton County Memorial Hospital
Camden Clark Medical Center
Fairmont Medical Center
Jackson General Hospital
Jefferson Medical Center
Potomac Valley Hospital
Reynolds Memorial Hospital
Summersville Regional Medical Center
St Joseph's Hospital
United Hospital Center
Wetzel County Hospital

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.