BENZODIAZEPINE WITH CONFIRMATION, RANDOM URINE

Test Code
LAB1231445


CPT Codes
80301

Includes
Urine benzodiazepine screen and urine creatinine. Auto-reflex to benzodiazepine confirmation by mass spectrometry if screen is positive.
Adulteration testing for urine creatinine is provided at no-charge and included in the report


Preferred Specimen
Urine, random specimen in a sterile plastic cup. No additives or preservatives.
Pediatric: Urine, random specimen in a sterled plastic cup. No additives or preservatives.


Minimum Volume
1mL Urine


Instructions
Required For Testing: 0.5 mL


Transport Temperature
Refrigerated


Specimen Stability
Ambient: 24 hours   Refrigerated: 5 days   Frozen: Not specified


Methodology
Enzyme Innumoassay (EIA)

Setup Schedule
Sunday- Saturday


Reference Range
Urine Benzodiazepine: Negative
Random Urine Creatinine: No Reference Range Established
 


Clinical Significance
Interpretive Information
Cutoff for positive value: 200 ng/mL
Approximate Detection Time In Urine: 3-8 days
Calibrator: Oxazepam

Lowest Drug Concentrations producing a POSITIVE RESULT
Compound Concentration  Tested (ng/mL)
Alprazolam 85
Alprazolam glucuronide 200
7-Aminoclonazepam 2,500
Bromazepam 170
Clorazepate 85
Chloridazepoxide 750
Clobazam 110
Clonazepam 150
Delorazepam 110
Desmethyldiazepam 75
Diazepam 70
Flunitrazepam 95
Flurazepam 100
Lorazepam 650
Lormetazepam 225
Medazepam 170
Nitrazepam 175
Norfludiazepam 85
Oxazepam glucuronide 40,000
Prazepam 95
Temazepam 115
Temazepam glucuronide 7,500
Triazolam 90

Concentrations of the following drugs produce a NEGATIVE RESULT on this test
 
Compound Concentration  Tested (ng/mL)
Acetaminophen 1,000
Acetylsalicylic Acid 1,000
Amphetamine 1,000
Caffeine 100
Codeine 1,000
Dextromethorphan 1,000
Diphenhydramine 500
Fluoxetine 500
Lorazepam glucuronide 50,000
Methadone 1,000
Morphine 200
Norfluoxetine 500
Norsertraline 300
Oxaprozin 50
Paroxetine 500
Phenycyclidine 1,000
Propoxyphene 1,000
Secobarbital 1,000
Sertraline 500


All results require interpretation with the patient’s clinical context (ie, disease states) in mind. Creatinine: results <30 mg/dL generally suggest that the specimen is overly dilute. This can result in falsely low drug screen results


Performing Laboratory
West Virginia University Hospital, Inc.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.