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ESTROGEN/PROGESTERONE (ER/PR) RECEPTOR, IMMUNOHISTOCHEMISTRY (IHC)
MessageThis test is ordered by pathologists.Guiding decisions on hormonal therapy in patients with carcinoma
Test Code
1230300848
CPT Codes
88342-TC, primary (Qualitative), 88360 (Quantitative)
Preferred Specimen
Tissue
Methodology
Immunohistochemistry (IHC)
FDA Status
This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufactureer's instructions. Performance characteristics were verified by WVUH in a manner consistent with CLIA requirements.
Clinical Significance
Estrogen receptor (ER) and progesterone receptor (PR), are steroid hormone receptors commonly used in managing women with breast cancer. ER and PR status provide an indication of prognosis and of the potential benefit from hormonal therapy. Generally, ER/PR-positive tumors are more likely to respond to endocrine therapy and have a better prognosis, stage-for-stage, than receptor-negative tumors. The test is infrequently used for non-breast cancer specimens.
Performing Laboratory
West Virginia University Hospitals, Inc.