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LITHIUM LEVEL
Test CodeLAB29
CPT Codes
80178
Preferred Specimen
One 6 mL red top tube
Pediatric Volume : One red to microtainer
Pediatric Volume : One red to microtainer
Other Acceptable Specimens
Dark green or gold top tube
Instructions
Sample must be centrifuged within two hours of collection. Serum/plasma (red or dark green top tube) must be removed from the red cells and put into aliquot tubes following centrifugation.
Transport Temperature
Refrigerated
Specimen Stability
Unstable, centrifuge within two hours of collection
Ambient: 24 hours
Refrigerated: 7 days
Frozen: 6 months
Ambient: 24 hours
Refrigerated: 7 days
Frozen: 6 months
Methodology
Colorimetric
Setup Schedule
Sunday-Saturday
Reference Range
Therapeutic: 0.60-1.20 mmol/L
Toxic levels (Critical value): >=1.5 mmol/L
Toxic levels (Critical value): >=1.5 mmol/L
Clinical Significance
Lithium therapy requires ~5 days to reach steady state (half-life ~ 18 hours).
Trough levels are drawn 8-12 hours after the previous dose (immediately prior to the next dose). Levels are initially drawn every 4-5 days after initiating therapy. Once clinical status and drug levels are stable, levels are checked every 1-3 months as clinically indicated.
Consider monitoring renal and thyroid function.
Trough levels are drawn 8-12 hours after the previous dose (immediately prior to the next dose). Levels are initially drawn every 4-5 days after initiating therapy. Once clinical status and drug levels are stable, levels are checked every 1-3 months as clinically indicated.
Consider monitoring renal and thyroid function.
Performing Laboratory
West Virginia University Hospital, Inc.
Berkeley Medical Center Camden Clark Medical Center Jefferson Medical Center Princeton Community Hospital Reynolds Memorial Hospital United Hospital Center Uniontown Hospital Wetzel County Hospital Wheeling Hospital