| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
PROSTATE-SPECIFIC ANTIGEN (PSA) TOTAL WITH FREE PSA REFLEX
Test CodeLAB1230024
CPT Codes
84153, 84154
Preferred Specimen
One 5 mL gold top tube
Pediatric: One gold top microtainer
Pediatric: One gold top microtainer
Minimum Volume
5 mL blood(Adult)
Required for Testing: 1mL serum
Required for Testing: 1mL serum
Other Acceptable Specimens
Red top tube
Instructions
Sample must be centrifuged within 2 hours of collection. Serum must be removed from the red cells and put into aliquot tubes following centrifugation.
Transport Temperature
Refrigerated
Specimen Stability
Centrifuge within 2 hours after collection
Ambient: Not Specified
Refrigerated: 24 hours
Frozen: not specified
Ambient: Not Specified
Refrigerated: 24 hours
Frozen: not specified
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Turbid, lipemic, grossly hemolyzed, or heat-inactivated specimens
Methodology
Chemiluminescent Microparticle Immunoassay
Setup Schedule
Sunday-Saturday
Reference Range
| Males Age | Free PSA Reference Range (ng/mL) |
| < 6 months | <0.10 |
| 6 months- 11 years | <0.35 |
| 12-19 years | <0.56 |
| ≥20 years | <2.50 |
Clinical Significance
The ratio of PSA existing in the free form (free:total PSA ratio) is useful in assessing the risk of prostate cancer in patients with borderline or
moderately increased total PSA (4.0-10.0 ng/mL) and has been used to help select men who should have a follow-up prostate biopsy.
Free PSA is not intended to be tested alone (i.e. without a total PSA level) and is not indicated in men with normal PSA results.
Free PSA is intended to be used to derive the free PSA ratio when measured with total PSA. Lower free PSA ratios (eg, < 0.15) correlate
with greater likelihood of positive prostate biopsy results. However, there is significant overlap between healthy and diseased patients with
regard to free PSA ratio.
moderately increased total PSA (4.0-10.0 ng/mL) and has been used to help select men who should have a follow-up prostate biopsy.
Free PSA is not intended to be tested alone (i.e. without a total PSA level) and is not indicated in men with normal PSA results.
Free PSA is intended to be used to derive the free PSA ratio when measured with total PSA. Lower free PSA ratios (eg, < 0.15) correlate
with greater likelihood of positive prostate biopsy results. However, there is significant overlap between healthy and diseased patients with
regard to free PSA ratio.
Performing Laboratory
West Virginia University Hospital, Inc.
Berkeley Medical Center Braxton County Memorial Camden Clark Medical Center Potomac Valley Hospital Reynolds Memorial Hospital Summersville Regional Medical Center St. Joseph’s Hospital United Hospital Center Uniontown Hospital Wetzel County Hospital
