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PROTEINASE 3 ANTIBODIES, IGG, SERUM
Test CodeLAB1459
CPT Codes
86235
Includes
If test result is positive, a sample will be sent for Cytoplasmic Neutrophil Antibodies testing.
Preferred Specimen
Gold Top Tube
Pediatric: 2 Gold top Microtainers
Pediatric: 2 Gold top Microtainers
Minimum Volume
Required for Testing: 0.5 mL
Other Acceptable Specimens
Red Top Tube
Instructions
Centrifuge within 1 hour of collection. Separate serum from cells if Red Top Tube. Aliquot 0.5 mL serum.
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated: 2-8°C 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Failure to fully fill tube.
Methodology
Multiplex Immunoassay
Setup Schedule
Tuesday and Thursday Dayshift
Reference Range
Negative
Clinical Significance
Evaluating patients suspected of having Wegener granulomatosis (WG)
Distinguishing between WG and other forms of vasculitis, inconjunction with Myeloperoxidase IgG Antibodies and ANCA/ Cytoplasmic Neutrophil Antibodies
May be useful to follow treatment response or to monitor disease activity in patients with myeloperoxidase antibodies
If test result is positive or equivocal, a sample will be sent for Cytoplasmic Neutrophil Antibodies testing.
Distinguishing between WG and other forms of vasculitis, inconjunction with Myeloperoxidase IgG Antibodies and ANCA/ Cytoplasmic Neutrophil Antibodies
May be useful to follow treatment response or to monitor disease activity in patients with myeloperoxidase antibodies
If test result is positive or equivocal, a sample will be sent for Cytoplasmic Neutrophil Antibodies testing.
Performing Laboratory
West Virginia University Hospital, Inc.
