ANCA VASCULITIS PANEL, IGG, SERUM

Test Code

LAB1250

CPT Codes
86235

Includes

LAB1362 Myeloperoxidase Antibodies, IgG and LAB1459 Proteinase 3 Antibodes IgG
If either the MYELOPEROXIDASE or PROTEINASE 3 antibody tests are postive or equivocal, a sample will be sent to Quest labs for
Cytoplasmic Neutrophil Antibody testing (ANCA).

Preferred Specimen

Gold Top Tube
Pediatric: Two gold top microtainers

Other Acceptable Specimens

Red Top Tube

Instructions

Centrifuge within 1 hour of collection. Separate serum from cells if Red top tube. Aliquot 0.5 mL serum.
Required for testing: 0.5 mL

Transport Temperature

Refrigerated

Specimen Stability

Refrigerated: 2-8°C 7days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Failure to fully fill tube.

Methodology
Multiplex Immunoassay

Setup Schedule

Tuesday, and Thursday, Dayshift

Reference Range

Negative

Clinical Significance

Useful for evaluating patients suspected of having Wegener granulomatosis (WG). Distinguishing between WG and other forms of vasculitis, in conjunction with Myeloperoxidase IgG Antibodies and ANCA/ Cytoplasmic Neutrophil Antibodies May be useful to follow treatment response or to monitor disease activity in patients with myeloperoxidase antibodies. Evaluating patients suspected of having immune-mediated vasculitis,especially microscopic polyangitis (MPA), when used in conjunction with other autoantibody tests. May be useful to follow treatment response or to monitor disease activity in patients with MPA.

Performing Laboratory
West Virginia University Hospitals, Inc.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.