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RNP ANTIBODIES, IGG, SERUM
MessagePlease see the test change notification for additional information
Test Code
LAB304228
CPT Codes
86235
Includes
Now distinctly separate from SMRNP detection. Recognizes RNP-A and RNP-68, if either is positive, the RNP is positive.
Preferred Specimen
Gold Top Tube
Pediatric: 2 Gold Top Microtainers
Pediatric: 2 Gold Top Microtainers
Minimum Volume
0.5 mL serum
Other Acceptable Specimens
Red Top Tube
Instructions
Centrifuge within 1 hour of collection. Separate serum from cells if Red Top Tube. Aliquot 0.5 mL serum.
Transport Temperature
Refrigerated
Specimen Stability
Refrigerated 2-8°C 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Failure to fully fill tubes.
Methodology
Multiplex Immunoassay
Setup Schedule
Monday - Friday Dayshift
Reference Range
Negative
Clinical Significance
Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive, especially those with signs and symptoms consistent with Sjogren's syndrome or systemic lupus erythematosus (SLE). Antinuclear sub-serology testing is NOT suggested unless a positive immunofluorescence result is obtained on initial ANA testing. Frequency of these antibodies in the non-diseased population is unknown and positivity does not necessarily suggest that a connective tissue disease is present.
Performing Laboratory
West Virginia University Hospital, Inc.
Additional Information
Test change notification
