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CRYPTOCOCCAL ANTIGEN, SERUM
MessageAids in the diagnosis of disseminated cryptococcosis caused by C.neoformans or C. gattii.
Test Code
LAB1230636
CPT Codes
87899
Includes
Lateral Flow Assay (LFA) test for the antigen of Cryptococcus neoformans
Preferred Specimen
Serum in a sterile vial (Serum Separatoror Red top)
Minimum Volume
0.5 mL Serum
Instructions
Specimen Stability
Refrigerated, 2-8°C for 72 hours.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
More than one specimen per patient submitted per week.
Methodology
Immunochromatographic lateral flow assay (IMMY)
Setup Schedule
Monday - Friday
Reference Range
Negative
Clinical Significance
Positive specimens are reflexed automatically to titer (range 1:1 – 1:2,560) and results verbally reported to licensed caregiver.
Monitoring of therapeutic response should not be based on titer (IDSA Guideline, Clin Infect Dis 2000;30:710).
Repeat testing of positive patients is limited to once per week.
Monitoring of therapeutic response should not be based on titer (IDSA Guideline, Clin Infect Dis 2000;30:710).
Repeat testing of positive patients is limited to once per week.
Performing Laboratory
J.W. Ruby Memorial Hospital