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OPIATES CONFIRMATORY/ DEFINITIVE, URINE, BY LC-MS/MS
Message- Definitive compliance checks in patients prescribed codeine, dihydrocodeine, hydrocodone, hydromorphone, morphine, oxycodone, and/or oxymorphone
- Confirming presumptive positive screening tests for opiates. [Urine quantitative values do NOT correlate well with serum concentrations and should not be used for assessing dose efficacy or timing.]
Test Code
LAB1230610
CPT Codes
80307
Includes
Quantitative/definitive detection of opiates that can cross-react and yield positive opiate screening results. Quantitative results are only provided for positive results; negative results will have an interpretation of “Negative” and a component result of “Not detected”. [Urine quantitative values do NOT correlate well with serum concentrations and should not be used for assessing dose efficacy or timing.]
Preferred Specimen
Urine, random specimen clean plastic collection cup
Minimum Volume
3mL
Instructions
Specimens collected in clean plastic collection cups are acceptable. Store refrigerated for best stability.
Transfer mixed urine specimen to a labeled red top tube and deliver to Chemistry department for track-based processing, adulteration testing,
and aliquoting for use in the mass spectrometry section.
Transfer mixed urine specimen to a labeled red top tube and deliver to Chemistry department for track-based processing, adulteration testing,
and aliquoting for use in the mass spectrometry section.
Transport Temperature
Refrigerated
Specimen Stability
Ambient: 3 days Refrigeared: 10 days
Methodology
LC-MS/MS
Setup Schedule
Monday thru Friday Dayshift
Reference Range
Negative
Clinical Significance
Cutoffs:
Codeine, 25 ng/mL
Dihydrocodeine, 25 ng/mL
Hydrocodone, 25 ng/mL
Hydromorphone, 25 ng/mL
Morphine, 25 ng/mL
Norhydrocodone, 25 ng/mL
Noroxycodone, 25 ng/mL
Oxycodone, 25 ng/mL
Oxymorphone, 25 ng/mL
Codeine, 25 ng/mL
Dihydrocodeine, 25 ng/mL
Hydrocodone, 25 ng/mL
Hydromorphone, 25 ng/mL
Morphine, 25 ng/mL
Norhydrocodone, 25 ng/mL
Noroxycodone, 25 ng/mL
Oxycodone, 25 ng/mL
Oxymorphone, 25 ng/mL
Performing Laboratory
West Virginia University Hospitals, Inc.
Additional Information
Test Change Notification
