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ANDROGEN RECEPTOR, IMMUNOHISTOCHEMISTRY (IHC)
MessageThis test is ordered by pathologists.
Test Code
1694339455
CPT Codes
88342-TC, primary, 88341-TC if additional IHC
Patient Preparation
Tissue
Other Acceptable Specimens
Formalin-fixed, paraffin-embedded (FFPE) tissue block
Methodology
Immunohistochemistry (IHC)
FDA Status
This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufactureer's instructions. Performance characteristics were verified by WVUH in a manner consisten with CLIA requirements.
Clinical Significance
Aid in diagnosing salivary duct carcinoma and in determining prostate origin in tumors of unknown primary.
Androgen receptor expression is broadly distributed across a variety of normal tissue types as well as in some carcinomas of the salivary
gland, breast, and prostate. Its primary use is in diagnosing salivary duct carcinoma and in determining prostate origin in tumors of
unknown primary. In prostate cancer, high expression of AR may be helpful in determining responsiveness to anti-androgen therapy. This
IHC may have other applications in certain breast carcinomas (apocrine), Paget’s disease and sebaceous carcinoma. Androgen
receptor IHC is a nuclear stain.
Androgen receptor expression is broadly distributed across a variety of normal tissue types as well as in some carcinomas of the salivary
gland, breast, and prostate. Its primary use is in diagnosing salivary duct carcinoma and in determining prostate origin in tumors of
unknown primary. In prostate cancer, high expression of AR may be helpful in determining responsiveness to anti-androgen therapy. This
IHC may have other applications in certain breast carcinomas (apocrine), Paget’s disease and sebaceous carcinoma. Androgen
receptor IHC is a nuclear stain.
Performing Laboratory
West Virginia University Hospitals, Inc.
