CHROMOSOME ANALYSIS, CONGENITAL DISORDER-PRODUCTS OF CONCEPTION

Test Code

LAB1238004

CPT Codes
88235, 88267, 88280, 88262, 88291

Includes

If sample does not grow, will be reflexed to Aneuvysion FISH if possible to rule out common aneuploidies of chromosomes 13, 18, 21, and X and Y.

Preferred Specimen

Identifiable fetal tissue-portion of thigh including skin, umbilical cord (1 nch section of umbilical cord with insertion point), 20mg villi from fetal side

Other Acceptable Specimens

Skin Sample: 2 mm thickness skin punch obtained aseptically in a sterile container containing RMPI 1640 or Hanks balanced salt solution (from Cytogenetic Lab) or saline ( not preferred but better than no fluid).Chorionic Villus: 20-50 mg chorionic villus sample (10-13 wks gestation) aspirated into a syringe containing RPMI 1640 or Hank's balanced salt solution (from Cytogenetic Lab) under aseptic conditions

Instructions

Place in the cytogenetic's bucket near chemistry. Take care to ensure tissue is fetal derived to avoid Maternal cell contamination. Small samples take longer to grow which may produce unwanted cultural artifacts.

Transport Temperature

Ambient or refrigerated (prolonged transport conditions) NEVER FROZEN

Specimen Stability

POC: Ambient (preferred) Refrigerated (prolong transport) NEVER FROZEN

Methodology
G-banded Karyotyping

Setup Schedule

Samples processed Monday through Saturday.

Report Available

Results reported Monday through Friday

Reference Range

An interpretive report will be provided

Performing Laboratory
West Virginia University Hospital, Inc.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.