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PLASMA CELL DISORDER (MYELOMA), FISH
Test CodeLAB1238021
CPT Codes
882718 x8-18, 88275 x5-10
Includes
If plasma cells <2%sample maybe QNS.
Preferred Specimen
Bone Marrow: 1 mL aspirate (sodium heparin)
Minimum Volume
Bone Marrow: 0.5mL aspirate (sodium heparin) *Minimum volume required depends on plasma cell concentration in the sample. This is the minimum volume for FISH only. Karyotype requires 0.5- 1.0 mL of its own.
Instructions
Place in cytogenetics bucket near chemistry.
Transport Temperature
Ambient or refrigerated (prolonged transport conditions) NEVER FROZEN
Specimen Stability
Bone Marrow:: Ambient(preferred), Refrigerated (acceptable) NEVER FROZEN
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Insufficient or clotted sample, more than 4 days old when received in laboratory.
Methodology
Fluorescent In Situ Hybridization (FISH) (Panel includes the following probes: D13S319, TP53, CKSIB/CDKN2C, Hyperdisplidy (+5, +9, +15), IGH, IGH/FGFR3, IGH/CCNDI, IGH/MAF, IGH/MYC, IGH/MAFB)
Setup Schedule
Samples processed Monday through Saturday. Results reported
Monday through Friday
Monday through Friday
Reference Range
An interpretive report will be provided
Performing Laboratory
West Virginia University Hospital, Inc.