A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
FIBRINOGEN
Test CodeLAB314
CPT Codes
85384
Preferred Specimen
One 3 mL blue top tube
Pediatric: One 1.8 mL pediatric blue top tube
Pediatric: One 1.8 mL pediatric blue top tube
Minimum Volume
1 mL Plasma
Instructions
Tube must be filled to etched line to perform testing.
Samples must be centrifuged at 3000 rpm for 10 minutes or using a high-speed centrifuge. Platelet poor plasma should be separated into 1 ml aliquots. Samples should be frozen within one hour (best practice), however samples stable for 4 hours. Samples must remain frozen during transport. Any samples that are received thawed are not suitable for testing.
Samples must be centrifuged at 3000 rpm for 10 minutes or using a high-speed centrifuge. Platelet poor plasma should be separated into 1 ml aliquots. Samples should be frozen within one hour (best practice), however samples stable for 4 hours. Samples must remain frozen during transport. Any samples that are received thawed are not suitable for testing.
Specimen Stability
Ambient: 4 hours if cap has not been removed or punctured
Frozen: 6 months (-70C)
Frozen: 6 months (-70C)
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted specimen, underfilled tube, or gross hemolysis.
Methodology
Optical density by Clauss method on ACL TOP. This is a fibrinogen ACTIVITY assay.
Setup Schedule
Sunday-Saturday
Reference Range
Adult: 200-400 mg/dL
<18 years old: 120-450 mg/dL
<18 years old: 120-450 mg/dL
Clinical Significance
Fibrinogen levels are useful for detecting increased or decreased fibrinogen levels of acquired or congenital origin. It is also useful for monitoring the severity and treatment of disseminated intravascular coagulation and fibrinolysis.
Performing Laboratory
West Virginia University Hospital, Inc.
Berkeley Medical Center Camden Clark Medical Center Camden Clark Medical Center Garrett Regional Medical Center Jackson General Hospital Jefferson Medical Center Princeton Community Hospital Reynolds Memorial Hospital United Hospital Center Uniontown Hospital Wheeling Hospital