D-DIMER

Test Code

LAB313

CPT Codes
85379

Preferred Specimen

One 3.0 mL blue top tube
Pediatric: One 1.8 mL pediatric blue top tube.

Minimum Volume

Required for Testing: 1 mL plasma

Instructions

Tube must be filled to etched line to perform testing.
Samples must be centrifuged at 3000 rpm for 10 minutes or using a high-speed centrifuge. Platelet poor plasma should be separated into 1 ml aliquots. Samples should be frozen within one hour (best practice), however samples stable for 4 hours. Samples must remain frozen during transport. Any samples that are received thawed are not suitable for testing.

Transport Temperature

Frozen (1 mL plasma aliquot)

Specimen Stability

Ambient: 4 hours if cap has not been removed or punctured
Frozen: 6 months (-70C)

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Clotted specimen, underfilled tube or gross hemolysis.

Methodology
Turbidimetric immunoassay on ACL TOP

Setup Schedule

Sunday-Saturday

Reference Range

≤500 ng/mL FEU

Clinical Significance

This assay has high sensitivity (100%) and negative predictive value (100%) for DVT and PE at a 500 ng/mL FEU cutoff according to the manufacturer. It has lower specificity depending on the pre-test probability of DVT or PE. Clinical Correlation is required.

Performing Laboratory
West Virginia University Hospital, Inc.
Berkeley Medical Center
Braxton County Memorial Hospital
Camden Clark Medical Center
Fairmont Medical Center
Jackson General Hospital
Jefferson Medical Center
Potomac Valley Hospital
Reynolds Memorial Hospital
Summersville Regional Medical Center
St Joseph's Hospital
United Hospital Center

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.