HIGH SENSITIVITY TROPONIN-I

LAB304150 (for ED only)

LAB139

One 4.5 mL light green top tube
Pediatric: One light green microtainer

Dark green top tube

Sample must be centrifuged within two hours of collection. Samples collected in a dark green (heparin) top tube must be removed from the red cells and put into aliquot tubes following centrifugation.

Refrigerated

Centrifuge within 2 hours of collection  
Ambient: 8 hours  
Refrigerated: 72 hours  
Frozen: 1 month

Samples collected in gold top or red top tubes

Sunday-Saturday

• 99th percentile reference cutoff for cardiac high-sensitivity Troponin I using Abbott Alinity i immunoasssay is gender- specific  (Expected results: Female, ≤14 ng/L; Male, ≤ 35 ng/L).
   
• Myocardial ischemia, injury and/or infarction should be differentiated using clinical factors and a rise and/or fall in serial cardiac troponin results, according to international consensus/ guidance documents. The recommended intreval between tests for establishing diagnosis in the acute setting is 2 to 3 hours.

Automatically Called Results (Critical Values)
> 14 ng/L (female) > 35 ng/L (male) for ED/ Observational Unit
> 300 ng/L for inpatients, outpatients, outreach samples (1st value within 24 hour period) 

Any condition resulting in myocardial cell damage can potentially increase cardiac troponin-I (TnI) levels. Published studies have documented that these conditions include, but are not limited to, acute myocardial infarction (AMI), angina, unstable angina, congestive heart failure, myocarditis, cardiac surgery, or invasive testing and noncardiac related causes such as pulmonary embolism, renal failure, and
sepsis. Serial sampling is recommended to detect the temporal rise and fall of troponin levels characteristic of AMI.