| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
CERULOPLASMIN, SERUM
Test CodeLAB304169
CPT Codes
82390
Preferred Specimen
One 5 mL Gold top tube
Other Acceptable Specimens
Red top tube
Instructions
Sample must be centrifuged within two hours of collection. Serum must be removed from the red cells and put into aliquot tubes following centrifugation. Required for Testing: 1 mL serum. Avoid freeze-thaw cycling
Transport Temperature
Refrigerated
Specimen Stability
Centrifuge within 2 hours after collection Ambient: 8 days Refrigerated: 2 weeks Frozen: 3 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Turbid or lipemic specimens
Methodology
Immunoturbidimetric
Reference Range
| AGE | Reference Values (mg/dL) |
| 0 days- 3 months | 5-18 |
| 4-6 months | 15-30 |
| 7-12 months | 33-43 |
| 1-7 years | 24-56 |
| ≥ 8 years | 18-45 |
Clinical Significance
Test useful for investigating patients with possible Wilson diseas. Ceruloplasmin is an acute phase protein and increases in acute or
chronic inflammation. It is also elevated in women taking oral contraceptives and estrogen supplements and during pregnancy.
Anticonvulsant therapies, methadone, tamoxifen and smoking also increase ceruloplasmin serum concentrations.
chronic inflammation. It is also elevated in women taking oral contraceptives and estrogen supplements and during pregnancy.
Anticonvulsant therapies, methadone, tamoxifen and smoking also increase ceruloplasmin serum concentrations.
Performing Laboratory
West Virginia University Hospital, Inc.
